N-Nitrosodiethylamine

SKU: orb1304080

Description

N-Nitrosodiethylamine (NDEA) is a potent carcinogenic nitrosamine found in various environmental and dietary sources. It is extensively used in research to induce experimental tumors, particularly hepatocellular carcinoma, in animal models for studying carcinogenesis, DNA damage, and chemoprevention strategies.

Research Area

Cell Biology, Molecular Biology

Key Properties

• CAS Number: 55-18-5
• MW: 102.14
• Purity: ≥98% (May vary between batches)
• Formula: C₄H₁₀N₂O
• SMILES: CCN(CC)N=O
• Target: DNA/RNA Synthesis
• Solubility: H2O:98 mg/mL (959.47 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (19.58 mM);DMSO:50 mg/mL (489.52 mM)

Bioactivity

• In Vivo:
  Mice with N-Nitrosodiethylamine (25mg/kg) intraperitonially resulted in fatty liver disease leading to progress of cancer disease.

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

N Nitrosodiethylamine, inhibit, Inhibitor, NDEA, NNitrosodiethylamine, N-Nitrosodiethylamine, DNASynthesis, DNA Synthesis, DNA/RNA Synthesis, Diethylnitrosamine, RNASynthesis, RNA Synthesis

Compound Identifiers

PubChem CID

5921