MMP13 (M) Antibody, Rabbit Polyclonal

SKU: orb66814

Description

Rabbit polyclonal to MMP13.Matrix metallopeptidase 13 (collagenase 3) (MMP13) is a zinc-dependent endopeptidase that belongsto the matrix metalloproteinase (MMP) family. Members of the MMP family are involved in thebreakdown of extracellular matrix in normal physiological processes, such as embryonic development,reproduction, migration and tissue remodeling. MMP13 has been implicated in disease progressions,including arthritis, chronic ulcers and metastasis. Most MMPs are secreted as zymogens requiringactivation by an extracellular proteinase. MMP13 cleaves type II collagen more efficiently than types Iand III. It may play a role in articular cartilage turnover and cartilage pathophysiology associated withosteoarthritis.

Research Area

Cardiovascular Disease, Epigenetics

Images & Validation

• Tested Applications: ELISA
• Dilution Range: ELISA:1:1000-1:10000
• Reactivity: Human

Key Properties

• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: middle region of human MMP13
• Molecular Weight: 54
• Purity: Affinity purification
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: 0.01% NaN3
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

anti-MMP13 antibody,anti-CLG3 antibody,anti-MANDP1 antibody

Quick Database Links

UniProt

P45452