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MK-2894

SKU: orb1709116

Description

MK-2894 is a selective prostaglandin receptor 4 (EP4) antagonist with demonstrated anti-inflammatory properties. It is utilized as a research tool for studying inflammation mechanisms in both in vitro cellular assays and in vivo animal models.

Research Area

Immunology & Inflammation, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number1006036-87-8
MW473.51
Purity99.22%
FormulaC25H22F3NO3S
SMILESCc1sc(C)c(C(=O)NC2(CC2)c2ccc(cc2)C(O)=O)c1Cc1ccc(cc1)C(F)(F)F
TargetProstaglandin Receptor
SolubilityDMSO:50 mg/mL (105.59 mM);H2O:< 1 mg/mL (Insoluble);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.22 mM)

Bioactivity

Target IC50
EP4:2.5 nM|EP4:0.56 nM (Ki)

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

EP4, MK 2894, MK2894, MK-2894, ProstaglandinReceptor, Prostaglandin Receptor

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Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

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Protocol Information

MK-2894 (orb1709116)

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

1 mg
$ 100.00
5 mg
$ 170.00
1 ml x 10 mM (in DMSO)
$ 180.00
10 mg
$ 270.00
25 mg
$ 600.00
50 mg
$ 1,020.00
100 mg
$ 1,330.00
500 mg
$ 2,670.00
DispatchUsually dispatched within 5-10 working days
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