MK-2894 sodium salt

SKU: orb1709117

Description

MK-2894 sodium salt is a potent and selective second-generation EP4 receptor antagonist. It is utilized in preclinical research to investigate prostaglandin E2 signaling in oncology and inflammation models, supporting both in vitro binding assays and in vivo efficacy studies.

Research Area

Immunology & Inflammation, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1006036-88-9
• MW: 496.5
• Purity: 99.22%
• Formula: C₂₅H₂₂F₃NNaO₃S
• SMILES: [Na].Cc1sc(C)c(C(=O)NC2(CC2)c2ccc(cc2)C(O)=O)c1Cc1ccc(cc1)C(F)(F)FjcExt:v:0:0
• Target: Others,Prostaglandin Receptor

Bioactivity

• Target IC50:
  EP4:0.56 nM (Ki)|EP4:2.5 nM (IC50)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

MK 2894 sodium salt, MK-2894 sodium, MK2894 sodium salt

Compound Identifiers

PubChem CID

68906166