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Mithramycin A

Mithramycin A

Catalog Number: orb1741464

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Catalog Numberorb1741464
CategorySmall Molecules
DescriptionMithramycin A
CAS Number18378-89-7
Purity0.9928
MW1085.15
SMILES[H][C@@]1(C[C@@H](O)[C@H](O)[C@@H](C)O1)O[C@@H]1C[C@]([H])(Oc2cc3cc4C[C@@]([H])([C@H](OC)C(=O)[C@@H](O)[C@@H](C)O)[C@H](O[C@@]5([H])C[C@@H](O[C@@]6([H])C[C@@H](O[C@@]7([H])C[C@](C)(O)[C@H](O)[C@@H](C)O7)[C@@H](O)[C@@H](C)O6)[C@H](O)[C@@H](C)O5)C(=O)c4c(O)c3c(O)c2C)O[C@H](C)[C@H]1O
FormulaC52H76O24
Biological ActivityMithramycin A (Plicamycin), a DNA-binding antitumor antibiotic, is a selective specificity protein 1 (Sp1) inhibitor, which inhibits the growth of various cancers by decreasing Sp1 protein. Specificity protein 1 (Sp1) is a zinc-finger transcription factor that regulates multiple cellular functions and promotes tumor progression.
Storage-20°C
NoteFor research use only
Expiration Date12 months from date of receipt.
  • Mithramycin [orb321638]

    ≥98%

    18378-89-7

    1084.47

    C52H76O25

    10 mg, 1 mg, 5 mg
  • Mithramycin A [orb545970]

    > 98%

    18378-89-7

    1085.15

    C52H76O24

    5 mg, 1 mg