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Melanin Concentrating Hormone, human, mouse, rat

SKU: orb2693907

Description

MCH (human, mouse, rat) is a potent peptide agonist of MCH-R and exhibits binding IC50 values of 0.3nM and 1.5 nM for MCH1R and MCH2R, respectively. MCH (human, mouse, rat) is a highly sensitive to MCH-2R in a CHO cell line and monitoring mobilization of intracellular calcium with FLIPR, exhibits functional activation EC50 values of 3.9 nM and 0.1nM for human MCH-1R and MCH-2R, respectively.

Images & Validation

Key Properties

TargetMCHR1 (GPR24)
Molecular Weight2386.8
Protein SequenceDFDMLRCMLGRVYRPCWQV (Disulfide bridge:Cys7-Cys16)
Purity≥95%

Storage & Handling

DisclaimerFor research use only

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Melanin Concentrating Hormone, human, mouse, rat (orb2693907)

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