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Maropitant

SKU: orb1220530

Description

Maropitant is a selective neurokinin (NK1) receptor antagonist.

Images & Validation

Key Properties

CAS Number147116-67-4
MW468.67
Purity>98% (HPLC)
FormulaC32H40N2O
SMILESCOc1ccc(cc1CN[C@H]1C2CCN(CC2)[C@H]1C(c1ccccc1)c1ccccc1)C(C)(C)C
TargetNeurokinin Receptor
SolubilityDMSO:33.33 mg/mL (71.12 mM)

Bioactivity

In Vivo
Treatment with 1 mg/kg Maropitant citrate, significantly reduces the size of ulcerative dermatitis (UD) lesions in mice. Intravenous Maropitant decreases MAC by 16%. In contrast, epidural administration of either saline or Maropitant does not change the MAC (2.17% and 1.92 %, respectively).

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information

Available Sizes

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2 mg
$ 90.00
5 mg
$ 130.00
10 mg
$ 210.00
25 mg
$ 320.00
50 mg
$ 590.00
100 mg
$ 870.00
500 mg
$ 1,880.00