m-PEG7-Br

SKU: orb1940647

Description

m-PEG7-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Key Properties

• CAS Number: 104518-25-4
• MW: 403.31
• Purity: >98% (HPLC)
• Formula: C₁₅H₃₁BrO₇
• SMILES: COCCOCCOCCOCCOCCOCCOCCBr
• Target: (HO)-1| Antifection| NF-κB| NO| NOS| Nrf2

Bioactivity

• In Vitro:
  PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

(HO)-1| Antifection| NF-κB| NO| NOS| Nrf2