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LXRA (M) Antibody, Rabbit Polyclonal
Catalog Number: orb67061
| Catalog Number | orb67061 |
|---|---|
| Category | Antibodies |
| Description | Rabbit polyclonal to LXRA.Liver X receptor alpha (LXRA) belongs to the nuclear hormone receptor family, NR1 subfamily. LXRAis an orphan receptor. LXRA can form a heterodimer with RXR, which shifts RXR from a silent DNAbindingpartner to an active ligand-binding subunit in mediating retinoid responses through targetgenes defined by LXRES. LXRES are DR4-type response elements characterized by direct repeats oftwo similar hexanuclotide half-sites spaced by four nucleotides. LXRA plays an important role in theregulation of cholesterol homeostasis, regulating cholesterol uptake through MYLIP-dependentubiquitination of LDLR, VLDLR and LRP8. |
| Species/Host | Rabbit |
| Clonality | Polyclonal |
| Tested applications | WB |
| Reactivity | Human, Mouse |
| Immunogen | middle region of human LXRA |
| Dilution range | WB:1:1000-1:5000 |
| Purity | Affinity purification |
| Conjugation | Unconjugated |
| MW | 50 |
| UniProt ID | Q13133 |
| Storage | -20°C |
| Buffer/Preservatives | 0.01% NaN3 |
| Alternative names | anti-LXRA antibody,anti-Oxysterols receptor LXRalp Read more... |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
Western blot analysis of total cell extracts from mouse liver using LXRA antibody
