Legionella pneumophila LPS (serogroup 1) mouse mAb Antibody

SKU: orb1946322

Description

Legionella pneumonia, first discovered after an outbreak in Pennsylvania in 1976 at the American Legion convention, is a common cause of community-acquired pneumonia. Legionella are gram-negative bacteria found in natural aquatic environments, where they are intracellular parasites of protozoa. The serogroup 1 strains most commonly cause human infections. Serotyping can be performed by antibody subgrouping, pulsed-field gele electrophoresis, or DNA sequencing. The lipopolysaccharide, LPS or endotoxin, of serogroup 1 is a bacterial virulence factor that contains 10-75 residues of the unique sugar termed legionaminic acid. Lacking free hydroxyl groups renders this LPS hydrophobic, allowing the bacterium to adhere to target cell membranes including macrophages in the lung.

Images & Validation

• Tested Applications: ELISA
• Dilution Range: 1µg/mL - 0.001µg/mL. It is recommended that the reagent be titrated for optimal performance for each application. See product image legends for additional information.
• Reactivity: Other

Key Properties

• Host: Rabbit
• Clonality: Monoclonal
• Isotype: Mouse IgG1k
• Clone No.: BCYD6EG6
• Immunogen: LPS conjugated to BSA
• Purification: Protein A+G
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: Liquid
• Buffer/Preservatives: 1X PBS, 0.02% NaN3, 50% Glycerol, 0.1% rAlbumin
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

AWB4CE4 antibody shows specific binding to LPS antigen from Legionella pneumophila (serogroup 1).