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LC3-mHTT-IN-AN1

SKU: orb1299237

Description

LC3-mHTT-IN-AN1

Research Area

Cell Biology, Pharmacology & Drug Discovery, Stem Cell & Developmental Biology

Images & Validation

Key Properties

CAS Number486443-73-6
MW411.04
Purity97.26% (May vary between batches)
FormulaC15H9Br2NO3
SMILESOc1cc(\C=C2/C(=O)Nc3ccc(Br)cc23)cc(Br)c1O
TargetATTECs|||Autophagy
SolubilityDMSO:120 mg/mL (291.94 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (9.73 mM)

Bioactivity

In Vitro
LC3-mHTT-IN-AN1 targeted mHTT to autophagosomes, reduced mHTT levels in an allele-selective manner, and rescued disease-relevant phenotypes in cells and in vivo in fly and mouse models of Huntington's disease.

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

ATTECs, Autophagy, Autophagosome-tethering compounds, inhibit, mHTT-LC3 Linker Compound, Inhibitor, LC3 mHTT IN AN1, LC3mHTTINAN1, LC-3-mHTT-IN-AN1, LC3-mHTT-IN-AN1

Similar Products

  • LC3-mHTT-IN-AN1 [orb1220248]

    >98% (HPLC)

    486443-73-6

    411.04

    C??H?Br?NO?

    5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 2 mg, 200 mg, 500 mg, 1 g
Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information

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1 ml x 10 mM (in DMSO)
$ 100.00
5 mg
$ 100.00
10 mg
$ 130.00
25 mg
$ 220.00
50 mg
$ 330.00
100 mg
$ 510.00
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