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JUN04542

SKU: orb1218340

Description

JUN04542 is an Axl Mer cMet KDR inhibitor for the treatment of Axl and Mer receptor tyrosine kinase- dependent disorders.

Images & Validation

Key Properties

CAS Number2367004-54-2
MW528.53
Purity>98% (HPLC)
FormulaC29H25FN4O5
SMILESCNC(=O)C1=CC2=C(C=CN=C2C=C1OC)OC3=CC=C(C=C3)NC(=O)C4(CC4)C(=O)NC5=CC=C(C=C5)F
Targetc-Met/HGFR
SolubilityDMSO:10 mM

Bioactivity

In Vivo
Animal model: Rat. Dosage: 3 mg/kg (Pharmacokinetic Analysis). Administration: IV. Result: Had a T1/2 of 5.4 hours, a CL of 43 mL/hr kg.

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

CL-092

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    2367004-54-2

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    5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 1 ml x 10 mM (in DMSO), 2 mg
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Protocol Information

JUN04542 (orb1218340)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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% DMSO +
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% Tween 80 +
%

Available Sizes

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200 mg
500 mg
5 mg
$ 190.00
10 mg
$ 280.00
25 mg
$ 610.00
50 mg
$ 890.00
100 mg
$ 1,250.00