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Catalog Number | orb1306457 |
---|---|
Category | Small Molecules |
Description | (+)-JQ-1 |
CAS Number | 1268524-70-4 |
Purity | 98.00% |
MW | 456.99 |
SMILES | CC=1C2=C(N3C([C@H](CC(OC(C)(C)C)=O)N=C2C4=CC=C(Cl)C=C4)=NN=C3C)SC1C |
Formula | C23H25ClN4O2S |
Biological Activity | (+)-JQ-1 (JQ1) is a BET bromine domain inhibitor that inhibits BRD4 (1/2) (IC50=77/33 nM) with specificity and reversibility. (+)-JQ-1 induces cell autophagy and inhibits cell proliferation. |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
[1505453-59-7] | |
445.9 | |
C24H20ClN5O2 |