JNJ-42165279

• Catalog Number: orb1304416
• Category: Small Molecules
• Description: JNJ-42165279
• CAS Number: 1346528-50-4
• Purity: 99.91%
• MW: 410.8
• SMILES: C(C=1C=C2C(=CC1)OC(F)(F)O2)N3CCN(C(NC=4C(Cl)=CC=NC4)=O)CC3
• Formula: C₁₈H₁₇ClF₂N₄O₃
• Biological Activity: JNJ-42165279 covalently inactivates the FAAH enzyme but is highly selective with regard to other enzymes, ion channels, transporters, and receptors. JNJ-42165279 (10 μM) exhibits high selectivity against a panel of 50 receptors, enzymes, transporters, and ion-channels, at which concentration it does not produce > 50% inhibition of binding to any of the targets. Fortunately, JNJ-42165279 (10 μM) also does not inhibit CYPs (1A2, 2C8, 2C9, 2C19, 2D6, 3A4) or hERG.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.