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Indophagolin

SKU: orb1219034

Description

Indophagolin is a potent, indoline-containing autophagy inhibitor with IC50 of 140 nM. Indophagolin antagonizes the purinergic receptor P2X4 as well as P2X1 and P2X3 with IC50s of 2.71, 2.40 and 3.49 μM, respectively.

Images & Validation

Key Properties

CAS Number1207660-00-1
MW523.75
Purity>98% (HPLC)
FormulaC19H15BrClF3N2O3S
SMILESO=S(C1=CC2=C(C=C1Br)CCN2C(C3CC3)=O)(NC4=CC=C(Cl)C(C(F)(F)F)=C4)=O
TargetAutophagy
SolubilityDMSO:10 mM

Bioactivity

In Vitro
Indophagolin (10 μM) inhibits autophagosome formation in MCF7 cells.

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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    1207660-00-1

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    1 mg, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 1 ml x 10 mM (in DMSO)
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Protocol Information

Indophagolin (orb1219034)

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Available Sizes

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200 mg
500 mg
2 mg
$ 230.00
5 mg
$ 330.00
10 mg
$ 480.00
25 mg
$ 790.00
50 mg
$ 1,110.00
100 mg
$ 1,520.00