IKZF3 degrader 1

SKU: orb2663699

Description

Compound 19a (IKZF3 Degrader 1) is a potent and effective molecular glue degrader of IKZF3, demonstrating an EC50 of 12 nM. It functions by recruiting IKZF3 to the CRBN E3 ubiquitin ligase, leading to its ubiquitination and proteasomal degradation. This tool compound is valuable for probing IKZF3 biology in hematological and immunological research contexts, both in vitro and in vivo.

Research Area

Immunology & Inflammation, Pharmacology & Drug Discovery

Images & Validation

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Key Properties

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MW	612.68
Formula	C₂₅H₁₈BrCl₃N₂O₅
Target	Others

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Others

Protocol Information

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MW:	527.06
Formula:	C₂₇H₃₅ClN₆O₃

MW:	896.43
Formula:	C₄₆H₅₄ClN₉O₈

CAS Number:	2226139-38-2
MW:	443.493
Formula:	C₂₃H₂₉N₃O₆

CAS Number:	5514-98-7
MW:	187.279
Formula:	C₁₀H₂₁NO₂

CAS Number:	2991817-99-1
MW:	288.3
Formula:	C₁₄H₁₆N₄O₃

IKZF3 degrader 1

Description

Research Area

Images & Validation

Key Properties

Storage & Handling

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