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HP1a (M) Antibody, Rabbit Polyclonal
Catalog Number: orb66782
| Catalog Number | orb66782 |
|---|---|
| Category | Antibodies |
| Description | Rabbit polyclonal to HP1a.Heterochromatin protein 1-alpha (HP1a) is a highly conserved nonhistone protein belonging to theheterochromatin protein family. The N-terminal chromodomain of HP1a binds to histone H3 tailsmethylated at Lys-9 (H3K9me), leading to epigenetic repression. Conversely, it is excluded fromchromatin when Tyr-41 of histone H3 is phosphorylated (H3Y41ph). It may interact with lamin-Breceptor. HP1a is involved in the formation of functional kinetochore through interaction with MIS12complex proteins. |
| Species/Host | Rabbit |
| Clonality | Polyclonal |
| Tested applications | WB |
| Reactivity | Human, Mouse |
| Immunogen | middle region of mouse HP1a |
| Dilution range | WB:1:1000-1:5000 |
| Purity | Affinity purification |
| Conjugation | Unconjugated |
| MW | 22 |
| UniProt ID | Q61686 |
| Storage | -20°C |
| Buffer/Preservatives | 0.01% NaN3 |
| Alternative names | anti-HP1a antibody,anti-Cbx5 antibody,anti-HP1 ant Read more... |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
Western blot analysis of total cell extracts from mouse thymus using HP1a antibody
