Hit 14

SKU: orb2646141

Description

Hit 14 is a potent CXCR4 inhibitor (IC50 = 254 nM) that impedes the migration and invasion of MDA-MB-231 cells in vitro by suppressing Akt phosphorylation. It also demonstrates anti-inflammatory and anti-metastatic potential, evidenced by its ability to reduce ear swelling and tissue damage in murine models.

Research Area

Cell Biology, Immunology & Inflammation, Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 440338-68-1
• MW: 496.60
• Formula: C₂₂H₂₈N₂O₇S₂
• SMILES: O=S(=O)(NCC1OCCC1)C2=CC=C(OC3=CC=C(C=C3)S(=O)(=O)NCC4OCCC4)C=C2
• Target: Akt,CXCR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

25039232