Heparin

SKU: orb1705503

Description

Heparin (Adomiparin) is a sulfated mucopolysaccharide widely employed as a clinical anticoagulant. It is utilized in research to investigate coagulation mechanisms and has demonstrated anti-inflammatory properties in various in vivo experimental models.

Research Area

Cell Biology, Infectious Disease & Virology, Metabolism Research, Protein Biochemistry

Key Properties

• CAS Number: 9005-49-6
• Target: Endogenous Metabolite,Antibacterial,Thrombin,Autophagy
• Solubility: DMSO:< 1 mg/mL (insoluble or slightly soluble);H2O:100 mg/mL

Bioactivity

• Target IC50:
  MT-4 cells:7.5 μg/mL
• In Vitro:
  Heparin, when administered for 6 days, demonstrates a reduction in the cytopathicity of HIV towards MT-4 cells, with an IC50 of 7.5 μg/mL. In SGHPL-4 cell line, Heparin at a concentration of 0.5 U/mL for 48 hours inhibits the hepatocyte growth factor (HGF)-induced trophoblast invasion.

Storage & Handling

• Storage: keep away from moisture,store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Adomiparin, Autophagy, Bacterial, Bemiparin, Certoparin, Dalteparin, Heparin, EndogenousMetabolite, Endogenous Metabolite, Thrombin

Compound Identifiers

PubChem CID

772