GLPG2938

SKU: orb1298289

Description

GLPG2938

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2130996-00-6
• MW: 503.4
• Purity: 98.10%
• Formula: C₂₀H₁₉F₆N₇O₂
• SMILES: CCOc1cc(NC(=O)NCc2cc(C)c(nn2)-c2cn(C)nc2C(F)(F)F)cc(n1)C(F)(F)F
• Target: S1P Receptor,LPL Receptor
• Solubility: DMSO:60 mg/mL (119.19 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.97 mM)

Bioactivity

• In Vivo:
  In all species ,GLPG2938 shows good pharmacokinetics, with long half-life,low clearance,and good bioavailability.
• In Vitro:
  GLPG2938 significantly prevents the S1P-mediated contraction at all tested concentrations.

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

S1P Receptor, S1P2, S1PReceptor, pulmonary, selective, potent, inhibit, Lysophospholipid Receptor, LPLReceptor, LPL Receptor, LPL, fibrosis, GLPG 2938, GLPG2938, GLPG-2938, Inhibitor, idiopathic, 1-(2-Ethoxy-6-(trifluoromethyl)pyridin-4-yl)-3-((5-methyl-6-(1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)pyridazin-3-yl)methyl)urea

Compound Identifiers

PubChem CID

137377911