Gcase activator 1

SKU: orb1302992

Description

LTI-291 is a potent and selective small molecule activator of the enzyme glucocerebrosidase (GCase). It is a valuable research tool for investigating GCase biology and its role in lysosomal storage disorders, including Gaucher disease and Parkinson's disease, in both cellular and animal models.

Research Area

Metabolism Research

Key Properties

• CAS Number: 1919820-28-2
• MW: 358.48
• Purity: 99.44% (May vary between batches)
• Formula: C₂₀H₃₀N₄O₂
• SMILES: CCCCCO[C@H]1CC[C@@H](CC1)NC(=O)c1cnn2c(C)cc(C)nc12
• Target: Glucosidase,glycosidase
• Solubility: DMSO:50 mg/mL (139.48 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.58 mM)

Bioactivity

• Target IC50:
  Gcase:

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Glucosidase, Gcase activator 1, Gcase activator1, Gcase activator-1, Inhibitor, inhibit, LTI 291, LTI291, LTI-291, β-glucosidase

Compound Identifiers

PubChem CID

121327414