Flopropione

SKU: orb1310530

Description

Flopropione, also known as Phloropropiophenone, is a small molecule antagonist of the 5-HT1A receptor with spasmolytic properties. It is utilized in pharmacological research to investigate serotonin receptor function in both in vitro binding assays and in vivo models of smooth muscle motility.

Research Area

Metabolism Research, Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2295-58-1
• MW: 182.17
• Purity: >99.99% (May vary between batches)
• Formula: C₉H₁₀O₄
• SMILES: CCC(=O)c1c(O)cc(O)cc1O
• Target: Transferase,5-HT Receptor
• Solubility: DMSO:55 mg/mL (301.92 mM);Ethanol:34 mg/mL (186.64 mM);H2O:< 1 mg/mL (insoluble or slightly soluble);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (10.98 mM)

Bioactivity

• In Vitro:
  Flopropione at temperatures below its T(g) shows no Lorentzian relaxation. Flopropione at temperatures below its T(g) has higher molecular mobility than Nifedipine. Flopropione shows Arrhenius temperature dependence throughout the entire temperature range and extrapolation of tau (beta) measured above T (g) by dielectric relaxation agreed with tau (beta) measured below T (g) by TAM/MDSC.

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Serotonin Receptor, Phloropropiophenone, COMT, 5-HT Receptor, 5-HT1A, 5HT Receptor, 5-hydroxytryptamine Receptor, 5HTReceptor, Inhibitor, inhibit, Flopropione

Compound Identifiers

PubChem CID

3362