Flopropione

SKU: orb1225591

Description

Flopropione is a spasmolytic or antispasmodic agent, and acts as a 5-HT1A receptor antagonist(In Vivo):The effect of Flopropione as an antispasmodic agent on the rate of passing a calculus from the urinary tract has been compared retrospectively with patients in whom passage was spontaneous. Flopropine has been shown, with statistical significance, to be superior to the control in cumulative passage rate after initiation of administration. Flopropine has been shown to exert a spasmolytic effect not only on smooth muscle of the gastrointestinal tract but also on smooth muscle of the pancreatobiliary and urinary systems.

Key Properties

• CAS Number: 2295-58-1
• MW: 182.18
• Purity: >98% (HPLC)
• Formula: C₉H₁₀O₄
• SMILES: CCC(=O)C1=C(O)C=C(O)C=C1O
• Target: 5-HT Receptor
• Solubility: Ethanol: 36 mg/mL (197.61 mM); DMSO: 36 mg/mL (197.61 mM)

Bioactivity

• In Vivo:
  The effect of Flopropione as an antispasmodic agent on the rate of passing a calculus from the urinary tract has been compared retrospectively with patients in whom passage was spontaneous. Flopropine has been shown, with statistical significance, to be superior to the control in cumulative passage rate after initiation of administration. Flopropine has been shown to exert a spasmolytic effect not only on smooth muscle of the gastrointestinal tract but also on smooth muscle of the pancreatobiliary and urinary systems.

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

5-HT Receptor