Farnesol

SKU: orb1299430

Description

Farnesol is a naturally occurring sesquiterpene alcohol with documented antibacterial properties. It is widely used in microbiological research for in vitro studies of biofilm inhibition and as a chemical probe for investigating bacterial quorum-sensing mechanisms.

Research Area

Infectious Disease & Virology, Metabolism Research

Key Properties

• CAS Number: 4602-84-0
• MW: 222.37
• Purity: 99.53%
• Formula: C₁₅H₂₆O
• SMILES: CC(C)=CCCC(C)=CCCC(C)=CCO
• Target: Antibiotic,Antibacterial,Endogenous Metabolite
• Solubility: DMSO:9 mg/mL (40.47 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (4.5 mM)

Bioactivity

• In Vivo:
  Farnesol, an acyclic sesquiterpene alcohol, is predominantly found in essential oils of various plants in nature, exhibit anti-cancer and anti-inflammatory effects, and also alleviate allergic asthma, gliosis, and edema. In numerous tumor cell lines, farnesol can modulate various tumorigenic proteins and/or modulates diverse signal transduction cascades. It can also induce apoptosis and downregulate cell proliferation, angiogenesis, and cell survival. To exert its anti-inflammatory/anti-oncogenic effects, farnesol can modulate Ras protein and nuclear factor kappa-light-chain-enhancer of activated B cells activation to downregulate the expression of various inflammatory mediators such as cyclooxygenase-2, inducible nitric oxide synthase, tumor necrosis factor alpha, and interleukin-6.

Storage & Handling

• Storage: keep away from direct sunlight,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Antibiotic, Bacterial, Inhibitor, Human Endogenous Metabolite, Endogenous Metabolite, EndogenousMetabolite, Farnesol, inhibit

Compound Identifiers

PubChem CID

3327