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Catalog Number | orb386163 |
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Category | Antibodies |
Description | Factor XIIIa has been identified in platelets, megakaryocytes, and fibroblast-like mesenchymal or histiocytic cells in the placenta, uterus, and prostate, monocytes and macrophages and dermal dendritic cells. Anti-Factor XIIIa has been found to be useful in differentiating between dermatofibroma (almost all cases are positive), dermatofibrosarcoma protuberans (-/+) and desmoplastic malignant melanoma (-). Anti-Factor XIIIa positivity is also seen in capillary hemagioblastoma, hemangioendothelioma, hemangiopericytoma, xanthogranuloma, xanthoma, hepatocellular carcinoma, glomus tumor, and meningioma. |
Clonality | Monoclonal |
Species/Host | Mouse |
Isotype | Mouse IgG2b, kappa |
Conjugation | Unconjugated |
Reactivity | Human |
Immunogen | A human partial recombinant protein corresponding to amino acids 46-181 was used as the immunogen for the Factor XIIIa antibody. |
UniProt ID | P00488 |
Tested applications | IHC-P, WB |
Dilution range | Western blot: 1-2ug/ml,Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT |
Application notes | Titering of the Factor XIIIa antibody may be required for optimal performance. |
Antibody Type | Primary Antibody |
Clone Number | SPM180 |
Formula | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Hazard Information | This Factor XIIIa antibody is available for research use only. |
Note | For research use only |
IHC testing of FFPE human placenta with Factor XIIIa antibody (clone SPM180). Required HIER: boil tissue sections in pH9 10mM Tris with 1mM EDTA for 10-20 min.
ELISA, FACS, IF, IHC-P, WB | |
Human | |
Mouse | |
Monoclonal | |
Unconjugated |