ER degrader 9

SKU: orb2646154

Description

Compound 1 (ER degrader 9) is a potent bifunctional degrader of the estrogen receptor, demonstrating a DC50 of ≤10 nM in MCF-7 breast cancer cells. It is a valuable research tool for investigating ERα biology and targeted protein degradation in breast cancer models, both in vitro and in vivo.

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 3023359-75-0
• MW: 616.83
• Formula: C₄₀H₄₈N₄O₂
• SMILES: OC=1C=C2C([C@H]([C@H](CC2)C3=CC=CC=C3)C4=CC=C(C=C4)N5CCC(CN6CCN(C(/C(=C\C(C)(C)C)/C#N)=O)CC6)CC5)=CC1
• Target: Molecular Glues,Estrogen Receptor/ERR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

170621047