ERD-308

SKU: orb1707962

Description

ERD-308 is a potent PROTAC degrader of estrogen receptor (ER), achieving >95% degradation at 5 nM with low DC50 values in ER+ breast cancer cell lines. It serves as a critical research tool for investigating targeted protein degradation in both in vitro and in vivo models of hormone receptor-positive cancers.

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2320561-35-9
• MW: 1004.26
• Formula: C₅₅H₆₅N₅O₉S₂
• SMILES: C(=O)(C1=C(SC=2C1=CC=C(O)C2)C3=CC=C(O)C=C3)C4=CC=C(OCCN(CCCCCOCC(N[C@H](C(=O)N5[C@H](C(N[C@@H](C)C6=CC=C(C=C6)C=7SC=NC7C)=O)C[C@@H](O)C5)[C@](C)(C)C)=O)CC)C=C4
• Target: Estrogen Receptor/ERR,PROTACs

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

138454799