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Dolasetron

SKU: orb1222843

Description

Dolasetron is a serotonin 5-HT3 receptor antagonist used to treat nausea and vomiting following chemotherapy. Its main effect is to reduce the activity of the vagus nerve, which is a nerve that activates the vomiting center in the medulla oblongata. It does not have much antiemetic effect when symptoms are due to motion sickness. This drug does not have any effect on dopamine receptors or muscarinic receptors.

Research Area

Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number115956-12-2
MW324.38
Purity>98% (HPLC)
FormulaC19H20N2O3
SMILES[H][C@]12C[C@@H](C[C@@H]3C[C@H](C1)C(=O)CN23)OC(=O)c1c[nH]c2ccccc12
Target5-HT3
SolubilityDMSO : ≥ 300 mg/mL; 924.87 mM

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

HSDB 7565 | HSDB7565 | Dolasetron | Dolasetronum

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Quality Guarantee

Quality Guarantee

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Protocol Information

Available Sizes

Select a size below

2 mg
$ 90.00
5 mg
$ 130.00
10 mg
$ 190.00
25 mg
$ 320.00
50 mg
$ 520.00
100 mg
$ 770.00
500 mg
$ 1,650.00