Direct Blue 1

SKU: orb1306148

Description

Direct Blue 1 (Pontamine Sky Blue) is a histological counterstain that reduces autofluorescence. It also functions as a selective, competitive inhibitor of vesicular glutamate transporters (VGLUTs) and has been identified as a small molecule ligand that inhibits the binding of Aβ to PrP. This makes it a useful tool for neuroscience research in both immunohistochemistry and synaptic transmission studies.

Research Area

Neuroscience, Signal Transduction

Key Properties

• Target: NF-κB,Beta Amyloid,GluR
• Molecular Weight: 992.8
• Purity: 50.00% (May vary between batches)
• CAS Number: 2610-05-1
• Formula: C₃₄H₂₄N₆Na₄O₁₆S₄
• SMILES: COc1c(ccc(c1)c1cc(c(cc1)/N=N/c1ccc2c(c1O)c(c(cc2S(=O)(=O)[O-])S(=O)(=O)[O-])N)OC)/N=N/c1ccc2c(c1O)c(c(cc2S(=O)(=O)[O-])S(=O)(=O)[O-])N.[Na+].[Na+].[Na+].[Na+]

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Inhibitor, glutamate, Glutamate Transporters, inhibit, autofluorescence, Chicago Sky Blue 6B, counterstain, Direct Blue1, Direct Blue-1, Direct Blue 1, Pontamine sky blue

Compound Identifiers

PubChem CID

17460