Direct Blue 1

• Catalog Number: orb1306148
• Category: Small Molecules
• Description: Direct Blue 1
• Purity: 50.00%
• MW: 992.8
• Biological Activity: Direct Blue 1 (Pontamine sky blue), a counterstain for background autofluorescence in immunofluorescence histochemistry, structurally resembles glutamate and operates as a potent, competitive VGLUT inhibitor, not impacting plasma membrane transporters. This compound stands out as the inaugural small molecule PrP ligand to inhibit Aβ binding.
• CAS Number: 2610-05-1
• Formula: C₃₄H₂₄N₆Na₄O₁₆S₄
• SMILES: COc1c(ccc(c1)c1cc(c(cc1)/N=N/c1ccc2c(c1O)c(c(cc2S(=O)(=O)[O-])S(=O)(=O)[O-])N)OC)/N=N/c1ccc2c(c1O)c(c(cc2S(=O)(=O)[O-])S(=O)(=O)[O-])N.[Na+].[Na+].[Na+].[Na+]
• Storage: -20°C
• Note: For research use only