Dihydroergotoxine mesylate

SKU: orb1297634

Description

Dihydroergotoxine mesylate, also known as ergoloid mesylates, is a research compound used to study age-related cognitive decline. Its applications include in vitro receptor binding assays and in vivo models investigating cerebral metabolism and blood flow.

Research Area

Metabolism Research, Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 8067-24-1
• MW: 423.53
• Purity: ≥95% (May vary between batches)
• Formula: C₂₀H₂₉N₃O₅S
• SMILES: CS(O)(=O)=O.[H][C@@]12CCCN1C(=O)[C@H](C(C)C)N1C(=O)[C@](C)(NC(=O)[C@@H]3CC4c5cccc6[nH]cc(C[C@@]4([H])N(C)C3)c56)O[C@@]21O.[H][C@@]12CCCN1C(=O)[C@H](CC(C)C)N1C(=O)[C@](C)(NC(=O)[C@@H]3CC4c5cccc6[nH]cc(C[C@@]4([H])N(C)C3)c56)O[C@@]21O.[H][C@@]12CCCN1C(=O)[C@H]([C@@H](C)CC)N1C(=O)[C@](C)(NC(=O)[C@@H]3CC4c5cccc6[nH]cc(C[C@@]4([H])N(C)C3)c56)O[C@@]21O.[H][C@@]12CCCN1C(=O)[C@H](Cc1ccccc1)N1C(=O)[C@](C)(NC(=O)[C@@H]3CC4c5cccc6[nH]cc(C[C@@]4([H])N(C)C3)c56)O[C@@]21O
• Target: Dopamine Receptor,PDE,GABA Receptor,Adrenergic Receptor,Chloride channel
• Solubility: DMSO:50 mg/mL;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL

Bioactivity

• Target IC50:
  Antiproliferative (prostate cancer cells):18-38 μM

Storage & Handling

• Storage: keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Dihydroergotoxine, Dihydroergotoxine mesylate, Dihydroergotoxine Mesylate, Inhibitor, Ergoloid mesylates, Gamma-aminobutyric acid Receptor, GABAReceptor, GABAR, GABA Receptor, inhibit, γ-Aminobutyric acid Receptor

Compound Identifiers

PubChem CID

154805971