Dihydroergotoxine mesylate

SKU: orb1221768

Description

Ergoloid Mesylates, also known as dihydroergotoxine mesylate, is a mixture of three dihydrogenated ergot alkaloids (dihydroergocristine, dihydroergocornine, and alpha- and beta-dihydroergocryptine). Ergoloid mesylates is used as a treatment for dementia and Alzheimer disease. Ergoloid Mesylates stimulates dopaminergic and serotonergic receptors and blocks alpha-adrenoreceptors. Ergoloid Mesylates binds to the GABAA receptor Cl- channel, producing a reaction at the benzodiazepine site.

Key Properties

• CAS Number: 8067-24-1
• MW: 673.82
• Purity: >98% (HPLC)
• Formula: C₃₃H₄₇N₅O₈S
• SMILES: CS(O)(=O)=O.CC(C)C[C@@H]1N2C(=O)[C@](NC(=O)[C@@H]3C[C@H]4[C@@H](Cc5c[nH]c6cccc4c56)N(C)C3)(O[C@@]2(O)[C@@H]2CCCN2C1=O)C(C)C
• Target: GSK-3
• Solubility: DMSO : ≥ 31 mg/mL; 13.39 mM

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Ergoloid Mesylates, Hydergine, Gerimal, CCK-179, CCK179

Quick Database Links

Gene Symbol

GSK-3