DGN462

SKU: orb1992886

Description

DGN462 is a DNA alkylating agent with demonstrated anti-tumor efficacy against acute myeloid leukemia (AML). It serves as a potent cytotoxic payload for antibody-drug conjugates (ADCs), with research applications in both in vitro cell studies and in vivo xenograft models for oncology drug development.

Research Area

Molecular Biology

Key Properties

• CAS Number: 1394079-41-4
• MW: 942.13
• Formula: C₅₃H₅₉N₅O₉S
• SMILES: O=C1N2C=3C(C[C@]2(CNC=4C1=CC(OC)=C(OCC5=CC(N(CCOCCOCCOC)CC(C)(C)S)=CC(COC6=C(OC)C=C7C(=C6)N=C[C@]8(N(C7=O)C=9C(C8)=CC=CC9)[H])=C5)C4)[H])=CC=CC3
• Target: ADC Cytotoxin

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

88930714