sulfo-DGN462 sodium

SKU: orb1691746

Description

Sulfo-DGN462 sodium is a prodrug that converts to the active DNA-alkylating agent DGN462 in physiological conditions. DGN462 demonstrates potent anti-tumor activity, particularly in acute myeloid leukemia (AML) research, with efficacy shown in both in vitro cellular assays and in vivo xenograft models.

Research Area

Molecular Biology

Key Properties

• CAS Number: 1401203-09-5
• MW: 1046.19
• Formula: C₅₃H₆₀N₅NaO₁₂S₂
• SMILES: [Na].[H][C@@]12Cc3ccccc3N1C(=O)c1cc(OC)c(OCc3cc(COc4cc5NC([C@]6([H])Cc7ccccc7N6C(=O)c5cc4OC)S(O)(=O)=O)cc(c3)N(CCOCCOCCOC)CC(C)(C)S)cc1NC2
• Target: DNA Alkylator/Crosslinker,ADC Cytotoxin

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

171360543