Deoxycytidine triphosphate

SKU: orb1219468

Description

Deoxycytidine triphosphate is a nucleoside triphosphate.It is a raw material in DNA synthesis. Deoxycytidine triphosphate has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing.

Key Properties

• CAS Number: 2056-98-6
• MW: 467.16
• Purity: >98% (HPLC)
• Formula: C₉H₁₆N₃O₁₃P₃
• SMILES: Nc1ccn([C@H]2C[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O2)c(=O)n1
• Target: Endogenous Metabolite
• Solubility: H2O:34 mg/mL(72.78 mM)

Bioactivity

• In Vitro:
  Assays of thirteen cell lines, derived from mouse lymphomas, myelomas, myeloid tumors, and a mastocytoma, for sensitivity to growth inhibition by 1-β-D-arabinofuranosylcytosine (ara-C) revealed a spectrum between the most and least sensitive which differed 100-fold from each other. An inverse correlation between sensitivity and cellular Deoxycytidine triphosphate (2′-Deoxycytidine-5′-triphosphate, dCTP) content is found, and this suggested that sensitivity of cells might be increased if the dCTP content was lowered during cell exposure to ara-C. Deoxycytidine triphosphate trisodium salt is a phosphoethanolamine cytidylyltransferase substrate.
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Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Endogenous Metabolite