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DDC-01-163

SKU: orb2814650

Description

DDC-01-163 is a potent and selective PROTAC molecule designed to degrade mutant EGFR proteins, demonstrating an IC50 of 45 nM. This compound is a valuable chemical tool for investigating mutant EGFR-driven cancers in both cellular and animal model studies.

Research Area

Cardiovascular Research, Pharmacology & Drug Discovery, Signal Transduction

Images & Validation

Key Properties

CAS Number2140806-84-2
MW942.05
FormulaC49H51N9O9S
SMILESO=C1NC(=O)C(N2C(=O)C=3C=CC=C(NCCOCCOCCOCCN4CCN(C=5N=CC(=CC5)C6=CC=C7C(=C6)C(=O)N(C7)C(C(=O)NC8=NC=CS8)C=9C=CC=CC9)CC4)C3C2=O)CC1
TargetEGFR,PROTACs

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

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Protocol Information

DDC-01-163 (orb2814650)

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