CCNA2 Antibody / Cyclin A2

SKU: orb534082

Description

CCNA2 is a Cyclin which controls both the G1/S and the G2/M transition phases of the cell cycle. Functions through the formation of specific serine/threonine protein kinase holoenzyme complexes with the cyclin-dependent protein kinases CDK1 or CDK2. The cyclin subunit confers the substrate specificity of these complexes and differentially interacts with and activates CDK1 and CDK2 throughout the cell cycle. [Uniprot]

Research Area

Epigenetics, Infectious Diseases

Images & Validation

• Tested Applications: IHC-P
• Dilution Range: IHC (FFPE): 1-2ug/ml for 30 min at RT
• Reactivity: Human
• Application Notes:
  Optimal dilution of the recombinant CCNA2 antibody should be determined by the researcher.

Key Properties

• Antibody Type: Primary Antibody
• Host: Mouse
• Clonality: Monoclonal
• Isotype: Mouse IgG2a, kappa
• Clone No.: CNA2-1
• Immunogen: Full length protein was used as the immunogen for this CCNA2 antibody.
• Purification: Protein G affinity chromatography
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: 0.2 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin and 0.05% sodium azide
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

IHC testing of FFPE human endometrial carcinoma with CCNA2 antibody (clone CNA2-1). Required HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.

Quick Database Links

UniProt

P20248