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CNQX

SKU: orb1220477

Description

CNQX is a competitive non-NMDA glutamate receptor antagonist (IC50s = 0.3 and 1.5 μM for AMPA and kainate receptors respectively).

Images & Validation

Key Properties

CAS Number115066-14-3
MW232.15
Purity>98% (HPLC)
FormulaC9H4N4O4
SMILES[O-][N+](=O)c1cc2[nH]c(=O)c(=O)[nH]c2cc1C#N
TargetGluR
SolubilityDMSO:30 mg/mL (129.23 mM)

Bioactivity

In Vivo
Animal model: Male Wistar rats weighing 180-200 g. Dosage: 0.75, 1.5, and 3 mg/kg. Administration: IP; 20 min before testing. Result: Decreased the number of cocaine (IV; 0.25 mg/infusion) responses in a dose-dependent manner during the first 15-min cocaine-free interval.

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

FG9065

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Protocol Information

CNQX (orb1220477)

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Step 1: Enter information below

(Recommended: An additional animal making an allowance for loss during the experiment)

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

500 mg
5 mg
$ 90.00
10 mg
$ 110.00
25 mg
$ 190.00
50 mg
$ 280.00
100 mg
$ 440.00
200 mg
$ 640.00