CKMT1 Antibody

• Catalog Number: orb1732562
• Category: Antibodies
• Description: Creatine kinase MT is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Creatine kinase MT occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase, this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80% homology with the coding exons of sarcomeric mitochondrial creatine kinase.
• Species/Host: Mouse
• Clonality: Monoclonal
• Tested applications: WB
• Reactivity: Human, Rat
• Isotype: Mouse IgG1
• Immunogen: Purified recombinant human CKMT1 protein fragments expressed in E.coli.
• Concentration: 1mg/ml
• Dilution range: WB: 1/500-1/1000
• Conjugation: Unconjugated
• MW: Calculated MW: 47 kDa; Observed MW: 47 kDa
• Entrez: 1159
• UniProt ID: P12532
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Buffer/Preservatives: Liquid in PBS containing 50% glycerol, 0.5% rAlbumin and 0.02% sodium azide, pH 7.3.
• Alternative names: CKMT; CKMT1; UMTCK; CKMT1A
• Note: For research use only
• Expiration Date: 12 months from date of receipt.