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CFTR corrector 4

SKU: orb1710080

Description

CFTR corrector 4

Research Area

Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number1918142-34-3
MW539.52
Purity99.32%
FormulaC29H27F2NO7
SMILESCOc1ccc2[C@@H](C[C@@H](Oc2c1)c1ccc(OC)c(OC)c1)NC(=O)C1(CC1)c1ccc2OC(F)(F)Oc2c1
TargetCFTR
SolubilityDMSO:50 mg/mL (92.67 mM)

Bioactivity

Target IC50
CFTR:(EC50)130 nM |CFTR:130 nM(EC50)
In Vitro
CFTR corrector 4 (Compound 13) possesses high potency and efficacy with an EC50 of 0.028 μM in HBE-TECC assay that assesses the CFTR function. CFTR corrector 4 is tested its potency and efficacy in human bronchial epithelial (HBE) cells with an EC50 value of 130 nM in the cell surface expression (CSE-HRP) assay.

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

CFTR, CFTR corrector 4

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Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

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Protocol Information

CFTR corrector 4 (orb1710080)

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

1 mg
$ 90.00
5 mg
$ 150.00
1 ml x 10 mM (in DMSO)
$ 170.00
10 mg
$ 210.00
25 mg
$ 380.00
50 mg
$ 520.00
100 mg
$ 720.00
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