Cephalothin

SKU: orb1301683

Description

Cephalothin is a beta-lactam antibiotic that acts as a potent inhibitor of the class C β-lactamase AmpC, with a Ki of 0.32 µM. It is used in research to study antibiotic resistance mechanisms and for in vitro assays evaluating β-lactamase inhibition and bacterial susceptibility.

Research Area

Infectious Disease & Virology

Key Properties

• CAS Number: 153-61-7
• MW: 396.44
• Purity: 99.62%
• Formula: C₁₆H₁₆N₂O₆S₂
• SMILES: C(O)(=O)C=1N2[C@@]([C@H](NC(CC3=CC=CS3)=O)C2=O)(SCC1COC(C)=O)[H]
• Target: Antibacterial,Antibiotic
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.04 mM);DMSO:60 mg/mL (151.35 mM)

Bioactivity

• Target IC50:
  β-lactamase AmpC:0.32 μM (Ki)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Cephalothin, Cephalotin, Cephalotin acid, Antibiotic, Bacterial, inhibit, Inhibitor, β-Lactamase

Compound Identifiers

PubChem CID

6024