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CeMMEC13

SKU: orb1300452

Description

CeMMEC13 is a selective isoquinolinone inhibitor of the TAF1 second bromodomain (IC50 = 2.1 µM). This chemical probe is used in vitro to study transcriptional regulation and has been applied in cellular models to investigate the biological functions of bromodomain-containing proteins.

Research Area

Cell Biology, Molecular Biology, Protein Biochemistry

Images & Validation

Key Properties

CAS Number1790895-25-8
MW336.34
Purity97.95% (May vary between batches)
FormulaC19H16N2O4
SMILESCn1c2ccccc2c(cc1=O)C(=O)Nc1ccc2OCCOc2c1
TargetDNA/RNA Synthesis,Carboxypeptidase
SolubilityEthanol:6 mg/mL (17.84 mM);DMSO:62 mg/mL (184.34 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.95 mM);H2O:< 1 mg/mL (insoluble or slightly soluble)

Bioactivity

Target IC50
TAF1:2.1 μM

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

DNA/RNA Synthesis, DNA Synthesis, DNASynthesis, CeMMEC 13, CeMMEC13, CeMMEC-13, Inhibitor, inhibit, TAF1, RNASynthesis, RNA Synthesis

Similar Products

  • CeMMEC13 [orb1225907]

    >98% (HPLC)

    1790895-25-8

    336.3

    C19H16N2O4

    25 mg, 50 mg, 5 mg, 100 mg, 200 mg, 500 mg, 1 g, 2 mg, 10 mg
Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information

Available Sizes

Select a size below

1 mg
$ 70.00
2 mg
$ 80.00
1 ml x 10 mM (in DMSO)
$ 110.00
5 mg
$ 110.00
10 mg
$ 160.00
25 mg
$ 300.00
50 mg
$ 420.00
100 mg
$ 540.00
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