Canertinib

Catalog Number: orb341542

Catalog Number	orb341542
Category	Small Molecules
Description	Canertinib (CI-1033) is a pan-ErbB inhibitor for EGFR and ErbB2 with IC50 of 1.5 nM and 9.0 nM, no activity to PDGFR, FGFR, InsR, PKC, or CDK1/2/4. Phase 3. CI-1033 shows excellent potency for irreversible inhibition of erbB2 autophosphorylation in MDA-MB
CAS Number	[267243-28-7]
MW	485.9444
SMILES	C=CC(NC1C=C2C(NC3=CC=C(F)C(Cl)=C3)=NC=NC2=CC=1OCCN1CCOCC1)=O
Formula	C₂₄H₂₅ClFN₅O₃
Note	For research use only
Expiration Date	12 months from date of receipt.

Chemical structure of Canertinib

Item 1 of 2
Canertinib, Dihydrochloride Salt [orb61004]
CAS Number:
289499-45-2
Sizes Available: 500 mg, 200 mg, 100 mg, 50 mg, 25 mg, 10 mg, 1 g
Item 1 of 1
Canertinib dihydrochloride [orb154663]
CAS Number:
[289499-45-2]
MW:
558.8603
Formula:
C₂₄H₂₇CL₃FN₅O₃
Sizes Available: 1 g, 100 mg, 250 mg, 10 mM * 1 mL in DMSO
Canertinib Dihydrochloride [orb609581]
Purity:
≥98%
CAS Number:
289499-45-2
MW:
558.86
Formula:
C₂₄H₂₃ClFN₅O₃ 2HCl
Sizes Available: 250 mg, 100 mg, 25 mg
Canertinib dihydrochloride [orb1225419]
Purity:
> 98% (HPLC)
CAS Number:
289499-45-2
Sizes Available: 10 mg, 5 mg, 200 mg, 100 mg, 50 mg, 1 g, 500 mg
Canertinib [orb1222438]
Purity:
> 98% (HPLC)
CAS Number:
267243-28-7
Sizes Available: 200 mg, 100 mg, 50 mg, 25 mg, 10 mg, 5 mg, 1 g, 500 mg

Purity:	> 98% (HPLC)
CAS Number:	267243-28-7