Boc-NH-PEG7-NH2

SKU: orb1940728

Description

Boc-NH-PEG7-NH2 is a PEG-based PROTAC linker.(In Vitro):PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein.

Key Properties

• CAS Number: 206265-98-7
• MW: 468.588
• Purity: >98% (HPLC)
• Formula: C₂₁H₄₄N₂O₉
• SMILES: CC(C)(C)OC(=O)NCCOCCOCCOCCOCCOCCOCCOCCN
• Solubility: In Vitro: DMSO : ≥ 250 mg/mL (533.53 mM)

Bioactivity

• In Vitro:
  PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only