Boc-NH-PEG3-NHS ester

SKU: orb1940667

Description

Boc-NH-PEG3-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Key Properties

• CAS Number: 2250216-93-2
• MW: 418.443
• Purity: >98% (HPLC)
• Formula: C₁₈H₃₀N₂O₉
• SMILES: CC(C)(C)OC(=O)NCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O
• Target: AChR| Beta Amyloid| ERK
• Solubility: In Vitro: DMSO : 50 mg/mL (119.49 mM)

Bioactivity

• In Vitro:
  PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

AChR| Beta Amyloid| ERK