Boc-NH-PEG3-CH2COOH

SKU: orb1218011

Description

Boc-NH-PEG3-CH2COOH is a PEG-based PROTAC linker can be used in the synthesis of PROTAC.

Key Properties

• CAS Number: 462100-06-7
• MW: 307.34
• Purity: >98% (HPLC)
• Formula: C₁₃H₂₅NO₇
• SMILES: O=C(OC(C)(C)C)NCCOCCOCCOCC(O)=O
• Target: PROTAC
• Solubility: In Vitro: DMSO : 100 mg/mL (325.37 mM)

Bioactivity

• In Vitro:
  PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

PROTAC