Boc-NH-O-C1-NHS ester

SKU: orb1217635

Description

Boc-NH-O-C1-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs.

Key Properties

• CAS Number: 80366-85-4
• MW: 288.25
• Purity: >98% (HPLC)
• Formula: C₁₁H₁₆N₂O₇
• SMILES: O=C1CCC(N1OC(CONC(OC(C)(C)C)=O)=O)=O
• Target: PROTAC
• Solubility: DMSO:10 mM

Bioactivity

• In Vitro:
  PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

PROTAC