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BMS986187

SKU: orb1217732

Description

BMS986187 is a novel Potent and Selective Positive Allosteric Modulators of the delta-Opioid Receptor.

Images & Validation

Key Properties

CAS Number684238-37-7
MW470.6
Purity>98% (HPLC)
FormulaC31H34O4
SMILESCC1=CC=CC=C1COC2=CC=C(C=C2)C3C4=C(CC(CC4=O)(C)C)OC5=C3C(=O)CC(C5)(C)C
TargetOpioid Receptor
SolubilityDMSO:10 mM

Bioactivity

In Vitro
BMS-986187 (1 nM-100 μM) produces little or no activity in agonist mode, but in PAM mode (in the presence of an EC20 of leu-enkephalin (in CHO-OPRD1 cells) or endomorphin 1 (in CHO-OPRM1 cells)) produces a response with an EC50 of 48 nM in CHO-OPRD1 cells and 2 μM in CHO-OPRM1 cells.

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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  • BMS986187 [orb1298464]

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    684238-37-7

    470.6

    C31H34O4

    5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 1 mg, 500 mg, 2 mg
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Protocol Information

BMS986187 (orb1217732)

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% DMSO +
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% Tween 80 +
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Available Sizes

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2 mg
$ 90.00
5 mg
$ 130.00
10 mg
$ 190.00
25 mg
$ 340.00
50 mg
$ 480.00
100 mg
$ 720.00
500 mg
$ 1,500.00