Bismuth subsalicylat

SKU: orb1226196

Description

Bismuth subsalicylate is used to treat diarrhea in adults and teenagers. It is also used to relieve the symptoms of an upset stomach, such as heartburn, indigestion, and nausea in adults and teenagers.

Key Properties

• CAS Number: 14882-18-9
• MW: 362.09
• Purity: >98% (HPLC)
• Formula: C₇H₅BiO₄
• SMILES: O=C1O[Bi](O)OC2=CC=CC=C12
• Target: COX
• Solubility: DMSO: 0.04 mg/mL (0.11 mM)

Bioactivity

• In Vivo:
  In the gastrointestinal tract, Bismuth Subsalicylate can be converted to salicylic acid and insoluble bismuth salts. Salicylic acid reduces inflammation/irritation of stomach and intestinal lining through inhibition of prostaglandin G/H synthase 1/2.Bismuth Subsalicylate (oral gavage; 100 mg/kg-350 mg/kg) significantly decreases castor oil-induced movement of a charcoal test meal along the small intestine of the mouse and rat and also decreases both the fecal output (dry or wet weight) and the frequency of diarrhea in mice.

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Bismuth oxide salicylate | Bismuth subsalicylate

Quick Database Links

Gene Symbol

COX