Benzoic acid

SKU: orb1310251

Description

Benzoic acid

Research Area

Infectious Disease & Virology, Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 65-85-0
• MW: 122.12
• Purity: 99.41% (May vary between batches)
• Formula: C₇H₆O₂
• SMILES: OC(=O)C1=CC=CC=C1
• Target: Antifungal|||Antibacterial|||Endogenous Metabolite
• Solubility: Ethanol:24 mg/mL (196.53 mM);H2O:< 1 mg/mL (insoluble or slightly soluble);DMSO:60 mg/mL (491.32 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (16.38 mM)

Bioactivity

• In Vivo:
  Under acidic growth conditions, Benzoic acid readily enters cells where its intracellular ionization significantly reduces both the intracellular pH and the levels of adenosine triphosphatase (ATPase). Benzoic acid is susceptible to oxidation by hydroxyl radicals produced by stimulated neutrophils. The average absorption of Benzoic acid through human skin shows no difference from that in rat studies, being minimally affected by skin thickness. The maximum rate of Benzoic acid transport across human skin cell membranes is 16.54 μg/cm2 per hour, with an actual dose of 70.6% in the receptor fluid after 24 hours.
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Fungal, FEMA 2131, FEMA2131, FEMA-2131, EndogenousMetabolite, Endogenous Metabolite, inhibit, Inhibitor, Bacterial, Dracylic acid, Benzoic acid

Compound Identifiers

PubChem CID

243