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Benzoic acid

SKU: orb1310251

Description

Benzoic acid

Research Area

Infectious Disease & Virology, Metabolism Research

Images & Validation

Key Properties

CAS Number65-85-0
MW122.12
Purity99.41%
FormulaC7H6O2
SMILESO=C(O)C=1C=CC=CC1
TargetAntifungal,Antibacterial,Endogenous Metabolite
SolubilityEthanol:24 mg/mL (196.53 mM);H2O:< 1 mg/mL (insoluble or slightly soluble);DMSO:60 mg/mL (491.32 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (16.38 mM)

Bioactivity

In Vivo
Under acidic growth conditions, Benzoic acid readily enters cells where its intracellular ionization significantly reduces both the intracellular pH and the levels of adenosine triphosphatase (ATPase). Benzoic acid is susceptible to oxidation by hydroxyl radicals produced by stimulated neutrophils. The average absorption of Benzoic acid through human skin shows no difference from that in rat studies, being minimally affected by skin thickness. The maximum rate of Benzoic acid transport across human skin cell membranes is 16.54 μg/cm2 per hour, with an actual dose of 70.6% in the receptor fluid after 24 hours.

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Fungal, FEMA 2131, FEMA2131, FEMA-2131, EndogenousMetabolite, Endogenous Metabolite, inhibit, Inhibitor, Bacterial, Dracylic acid, Benzoic acid

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Key Properties

No computed properties available.

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Benzoic acid (orb1310251)

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% Tween 80 +
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1 g
$ 70.00
1 ml x 10 mM (in DMSO)
$ 70.00
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