Basifungin

SKU: orb1218968

Description

Aureobasidin A is a cyclic peptide and an antifungal antibiotic. Aureobasidin A is an inhibitor of the inositolphosphorylceramide synthase AUR1.

Key Properties

• CAS Number: 127785-64-2
• MW: 1117.42
• Purity: >98% (HPLC)
• Formula: C₆₀H₉₂N₈O₁₂
• SMILES: CC(C)(O)[C@@]1(C(O1)=O)N(C([C@H](CC(C)C)NC([C@H](C(C)C)N(C([C@H]([C@H](C)CC)NC([C@H]2N(C([C@H](CC3=CC=CC=C3)N(C([C@H](CC4=CC=CC=C4)NC([C@H](C(C)C)N(C(C(O)C(C)CC)=O)C)=O)=O)C)=O)CCC2)=O)=O)C)=O)=O)C
• Target: Antifungal
• Solubility: In Vitro: DMSO : 100 mg/mL (90.79 mM)

Bioactivity

• In Vitro:
  Aureobasidin A arrests growth of yeast cells through both ceramide intoxication and deprivation of essential inositolphosphorylceramides.

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Aureobasidin A

Quick Database Links

Gene Symbol

Antifungal